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On top of that, malaria is prevalent in almost all areas of the Dominican Republic, except for the cities of Santo Domingo and Santiago. As an expat who plans on spending months or even years in the DR, it is likely that you will visit places in the Dominican Republic where the risk of an infection is particularly high. Thus, you should talk to your doctor about taking antimalarial drugs such as Atovaquone-proguanil, Chloroquine, Doxycycline, or Mefloquine. However, taking precautions can also be an effective way of preventing a malaria infection: make sure to use insect repellent, wear long sleeves and pants, and sleep in well-screened rooms or under bed nets.
Also, as of 2016, there is a warning issued against the Zika virus. This virus can be dangerous for pregnant women and is also transmitted by mosquitoes. It is therefore recommended to take the same precautions as for preventing a malaria infection and to contact your embassy for more information.